It has just been reported that a Germanwings (a Lufthansa subsidiary ) Airbus A320 crashed enroute from Barcelona to Dusseldorf. It appears to be flight 9525 that was scheduled to land in 11:25AM local time.
Reports state that there were 142 passengers and 6 crew members. For more details on flight path and more, see this article.
It is still early yet, but my thoughts and prayers are certainly with the families of those onboard and those who work to locate the crash and victims.